After graduating from Kedge Business School in Bordeaux, France, and from Reading University in the UK with a Master's degree in Economics and International Business, Valérie Agathon started off her career outside of her native France, first in Germany, then in Sweden. She then joined Dassault Systèmes as Head of Marketing Projects, then Head of Investor Relations, before moving up to Director of Investor Relations.

She joined the Bouygues Group in 2009 as Director of Investor Relations, then Director of Strategy and Development.

In 2019, she moved over to Colas as CFO of the Materials and Bitumen business units, before becoming, in 2021, Deputy Director of the Materials business unit and CFO of the Bitumen business unit.

In February 2023, Valérie Agathon was appointed Vice President, Administration, Finance and Strategy of the Colas Group. She reports directly to the Chairman and CEO.